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Nursing Article Review Paper on Pathophysiology

Nursing Article Review Paper on Pathophysiology Nursing Article Review Paper on PathophysiologyThe article titled the inflammation connection: the newly-discovered link between biological processes reveals a novel way to control inflammation, published on April 1, 2019, and authored by scientists at the Centre for Genomic Regulation (CRG) explains the existence of biological details regarding the production of critical molecules involved in inflammation. It is reported that the discovery points to an alternative paradigm for the development of anti-inflammatory drugs (Centre for Genomic Regulation, 2019). The mentioned research focused on IL-1β, a protein generated by the immune cells to respond to bacterial infections and tissue damage (Centre for Genomic Regulation, 2019). The protein molecule generated triggers inflammation essential to fighting infections, as well as accelerating the healing process. Per Hong, Kim & Im (2016), excessive production of IL-1β protein results in undesired inflammation responsible for a broad array of diseases. The production of the mentioned protein at the right time and place is necessary to enhance a person’s health and wellness.Nursing Article Review Paper on PathophysiologyORDER A PLAGIARISM-FREE PAPER HEREThis article connects to pathogenesis, an aspect of pathophysiology. In this regard, Chow & Chin (2020) opine that pathogenic factors such as infections and tissue damage induce inflammation. In response to the tissue damage, the immune system initiates chemical processes that provoke responses aimed at healing the affected body tissues. Centre for Genomic Regulation (2019) asserts the need to examine how to interfere with the pathways producing molecules essential in facilitating the therapeutic process. Importantly, Chen et al. (2017) claim understanding the Unfolded Protein Response (UPR) and IL-1β pathways provides evidence on how to manage the production of inflammatory molecules. Significantly, the evidence presented in the article is relevant to pathophysiology because drugs that block the UPR are currently in development stages with the aim of treating diseases like Alzheimer’s involving abnormal proteins. Additionally, the findings of the research are likely to be utilized in uncovering additional anti-inflammatory therapies.Nursing Article Review Paper on PathophysiologyReferencesCentre for Genomic Regulation. (2019). The inflammation connection: Newly-discovered link between biological processes reveals a novel way to control inflammation. Centre for Genomic Regulation. Retrieved from, L., Deng, H., Cui, H., Fang, J., Zuo, Z., Deng, J., Li, Y., Wang, X., & Zhao, L. (2017). Inflammatory responses and inflammation-associated diseases in organs. Oncotarget, 9(6), 7204–7218.Chow, Y., & Chin, K. (2020). The Role of Inflammation in the Pathogenesis of Osteoarthritis. Mediators of Inflammation, 2020, 8293921.Hong, H., Kim, B., & Im, H. (2016). Pathophysiological role of neuroinflammation in neurodegenerative diseases and psychiatric disorders. International Neurourology Journal, 20(Suppl 1), 1-7. Nursing Article Review Paper on Pathophysiology

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