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Analyzing and Synthesizing the Body of Evidence Essay

Analyzing and Synthesizing the Body of Evidence Essay Analyzing and Synthesizing the Body of Evidence EssayIn this assignment, you will take a critical look at the Evaluation Table and develop a Synthesis Table, which is the next step in finding the best evidence for your project. From the Evaluation Table, which represents the body of evidence for your topic, you will review the information and synthesize it into one or more tables paring down the body of evidence to the studies that are most appropriate for answering yourPICOT question;In Black and White adult patient with DM2 (P), how does utilizing EHR alerts based on HbA1c treatment goals and guidelines (I) compared to not utilizing EHR alerts based on HbA1c treatment goals and guidelines (C) influence the reduction of disparities (O) over a year (T)?The Synthesis Table Template has been provided that includes several different types of tables. Choose the tables that are most pertinent to this project. Review the PICOT question and the Evaluation Table of the quantitative evidence and complete it by adding the qualitative evidenceThen:Analyzing and Synthesizing the Body of Evidence Essay1.)Analyze the contents of the table. Which variables (column headings) are the most important to answering the PICOT question? Why?ORDER A PLAGIARISM-FREE PAPER HERE)Create the appropriate Synthesis Table (or tables) and turn it in for this assignment along with a 1- to 2-page paper providing:)A reason for including these variables in the Synthesis Table 4.)A rationale that explains how these variables are most appropriate for answering your PICOT question   Analyzing and synthesizing body of evidencePICOT question:“In Black and White adult patient with DM2 (P), how does utilizing EHR alerts based on HbA1c treatment goals and guidelines (I) compared to not utilizing EHR alerts based on HbA1c treatment goals and guidelines (C) influence the reduction of disparities (O) over a year (T)?”Analyzing and Synthesizing the Body of Evidence Essay1.) Analyze the contents of the tableBased on the contents of the evaluation table, there are five column headings that can be considered as most important for answering the PICOT question.The first important column is the design/method column that identifies the approach applied in collecting the research data. This is relevant in answering the PICOT question because it matches the objectives for significance. In essence, a study would be considered relevant if its purpose matches that presented in the PICOT question.The second important column is the sample and setting column that presents the number of participants and their demographics that acted as the inclusion criteria. This is relevant to answering the PICOT question because it talks to the P element of the question. Greater relevance is achieved when the populations in the research and PICOT question are matched.Analyzing and Synthesizing the Body of Evidence EssayThe third important column is the major variables column that identifies both the independent and dependent variables that guided the thematic analysis of the collected data. This column is relevant because it linked to the research purpose while creating the setting for the relationship between the treatment and approach and control as presented in the PICOT question. Presence of the treatment approach and control in the variables list is an indication that the research is significant in answering the PICOT question.The fourth important column is the findings column that presents the prevailing relationship between the variables. This column is relevant in answering the PICOT question because it offers a scientifically justified understanding of the treatment approach, in comparison to the control (assuming that the variables are matched for the research and PICOT question, and the methodology follows a scientifically accepted approach to include peer reviews).Analyzing and Synthesizing the Body of Evidence EssayThe final important column is the appraisal column that presents the evaluators opinion of the research value to include weaknesses, strengths, conclusion, feasibility, and use in answering the PICOT question. This column is relevant because it presents a justified and objective opinion of the research value in answering the PICOT question.2.) Create the appropriate Synthesis Table (or tables)Table 1: Synthesis table Arnold et al. (2018)Brateanu et al. (2017)Leiteerapong et al. (2017)Clements et al. (2014)Level of EvidenceLevel I: Systematic review or meta-analysis Analyzing and Synthesizing the Body of Evidence Essay  Level II: Randomized controlled trial    Level III: Controlled trial without randomization    Level IV: Case-control or cohort study    Level V: Systematic review of qualitative or descriptive studies    Level VI: Qualitative or descriptive study (includes evidence implementation projects) Analyzing and Synthesizing the Body of Evidence Essay  Level VII: Expert opinion    InterventionsUsing timely treatment intensification to control HbA1CDevelop a probability model and screening interval for diabetes in 2008, January 2009 and December 2013.Identify HbA1c trajectories for persons with type 2 diabetes.Identify predictors of poor glycemic control for diabeticsSample547 persons with type 2 diabetes whoseHbA1c level was ≥8.0% (64 mmol/mol) and whose medical information was available from the EHR of a large accountable care organization from July 2011 to June 20155084 participants from Cleveland Clinic Health System28,016 patients newly diagnosed with type 2 diabetes.Analyzing and Synthesizing the Body of Evidence Essay2,218 pediatrics with diabetes from Midwest USA between 1993 and 2009.OutcomeEffective control (Hba1c level <8.0%) achieved for males (OR 0.53 [P = 0.0165]) and treatment by internist. Hispanics had poor control (OR=2.91, P = 0.0304).Analyzing and Synthesizing the Body of Evidence EssayDiabetes incidence linked with  HbA1c (HR per 0.1 units increase 1.20; 95%CI, 1.13–1.27), family history (HR 1.31; 95%CI, 1.13–1.51), smoking (HR 1.18; 95%CI, 1.03–1.35), triglycerides (HR 1.01; 95%CI, 1.00–1.03), alanine aminotransferase (HR 1.07; 95%CI, 1.03–1.11), body mass index (HR 1.06; 95%CI, 1.01–1.11), age (HR 0.95; 95%CI, 0.91–0.99) and high-density lipoproteins (HR 0.93; 95% CI, 0.90–0.95).HbA1c trajectories identified as “low stable” (82.5%), “moderate increasing late” (5.1%), “high decreasing early” (4.9%), “moderate peaking late” (4.1%) and “moderate peaking early” (3.3%).Greater deterioration in control among older patients when compared to their younger counterparts.Non-Hispanic African-American patients experienced higher initial HbA1c (8.7% vs 7.6% (71.6 vs 59.6 mmol/mol); p<0.001), and greater deterioration in HbA1c than non-Hispanic Caucasian patients across diagnostic ages (rise of 2.04% vs 0.99% per year (22.3 vs 10.8 mmol/mol/year); p<0.0001).Analyzing and Synthesizing the Body of Evidence Essay3.& 4.) VariablesThe four variables (as presented in the synthesis table) are equally important in answering the PICOT question. Firstly, the level of evidence is important in identifying the research value as a tool for making recommendations. The implication is that lower levels of evidence are considered to be of higher evidentiary value in answering the PICOT question when compared to higher levels of evidence. Secondly, the intervention identifies the treatment approach that can then be matched to the PICOT question as the controllable variable. Thirdly, the sample identifies the population of interest. This is important since it can be matched to the P element of the PICOT question. Finally, the outcome notes the specific relationship between the variables for the population. This is important because it talks to the true value of the intervention when compared to the control as a factor of the desired outcome.Analyzing and Synthesizing the Body of Evidence Essay ReferencesArnold, R., Yang, S., Gold, E., Farahbakhshian, S. & Sheehan, J. (2018). Assessment of the relationship between diabetes treatment intensification and quality measure performance using electronic medical records. PLoS ONE, 13(6), e0199011. doi: 10.1371/journal.pone.0199011. Retrieved from http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199011Brateanu, A., Barwacz, T., Kou, L., Wang, S., Misra-Hebert,A. … & Rothberg, M. (2017) Determining the optimal screening interval for type 2 diabetes mellitus using a risk prediction model. PLoS ONE, 12(11), e0187695. doi: 10.1371/journal.pone.0187695. Retrieved from http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0187695Clements, M., Lind, M., Raman, S., Patton, S., Lipska, K. … &Kosiborod, M. (2014). Age at diagnosis predicts deterioration in glycaemic control among children and adolescents with type 1 diabetes. BMJ Open Diabetes Res Care, 2(1): e000039. doi: 10.1136/bmjdrc-2014-000039Laiteerapong, N., Karter, A, Moffet, H., Cooper, J., Gibbons, R. … & Huang, E. (2017). Ten-year hemoglobin A1c trajectories and outcomes in Type 2 diabetes mellitus: The Diabetes & Aging Study. J Diabetes Complications, 31(1), 94-100. doi: 10.1016/j.jdiacomp.2016.07.023. Analyzing and Synthesizing the Body of Evidence Essay

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